|Catalog No||Formulation||Size||Price (USD)|
|960-RBM10-P0||Purified Ab with BSA and Azide at 200ug/ml||20 ug||199.00|
|960-RBM10-P1||Purified Ab with BSA and Azide at 200ug/ml||100 ug||379.00|
|960-RBM10-P2||Purified Ab with BSA and Azide at 200ug/ml||200 ug||549.00|
|960-RBM10-P1ABX||Purified Ab WITHOUT BSA and Azide at 1.0mg/ml||100 ug||399.00|
|960-RBM10-P2ABX||Purified Ab WITHOUT BSA and Azide at 1.0mg/ml||200 ug||579.00|
|Human Entrez Gene ID||960|
|Human Gene Symbol||CD44|
|Human Chromosome Location||11p13|
|Synonyms||LHR; BA-1; chondroitin sulfate proteoglycan 8 (CSPG8); Epican; Extracellular Matrix Receptor III (ECM III); GP90 Lymphocyte Homing Adhesion Receptor; HCAM; HCELL; hematopoietic cell E- and L-selectin ligand; Heparan Sulfate Proteoglycan; Hermes Antigen; HAS; HUTCH I; Hyaluronate Receptor; Indian blood group; Inlu Related p80 Glycoprotein; Ly 24; MDU2; MDU3; MIC4; MUTCH I; Phagocytic Glycoprotein 1 (PGP-1)|
|Immunogen||Recombinant fragment corresponding to the v4 domain of human CD44 (exact sequence is proprietary)|
|Host / Ig Isotype||Rabbit / IgG, kappa|
|Mol. Weight of Antigen||80-95kDa|
|Cellular Localization||Cell surface|
|Species Reactivity||Human. Others-not tested.|
This antibody recognizes an epitope encoded by exon v4 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.
Flow Cytometry (0.5-1ug/million cells)
Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.
Cervix or Tongue Squamous Cell Carcinoma
200ug/ml of Ab purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
This antibody is available for research use only and is not approved for use in diagnosis.
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.