|Catalog No||Formulation||Size||Price (USD)|
|1113-RBM11-P0||Purified Ab with BSA and Azide at 200ug/ml||20 ug||199.00|
|1113-RBM11-P1||Purified Ab with BSA and Azide at 200ug/ml||100 ug||379.00|
|1113-RBM11-P2||Purified Ab with BSA and Azide at 200ug/ml||200 ug||549.00|
|1113-RBM11-P1ABX||Purified Ab WITHOUT BSA and Azide at 1.0mg/ml||100 ug||399.00|
|1113-RBM11-P2ABX||Purified Ab WITHOUT BSA and Azide at 1.0mg/ml||200 ug||579.00|
|Human Entrez Gene ID||1113|
|Human Gene Symbol||CHGA|
|Human Chromosome Location||14q32.12|
|Synonyms||Beta-Granin; CGA; CHGA; Chromogranin A Parathyroid Secretory Protein 1; ER-37; Pancreastatin; Parastatin; Parathyroid Secretory Protein 1; Pituitary Secretory Protein I; SP-I; Vasostatin I or II|
|Immunogen||Recombinant human full-length Chromogranin A protein|
|Host / Ig Isotype||Rabbit / IgG, kappa|
|Mol. Weight of Antigen||68-75kDa|
|Cellular Localization||Finely granular cytoplasmic|
|Species Reactivity||Human. Does not react with rat. Others not known.|
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Flow Cytometry (0.5-1ug/million cells)
Immunohistology (Formalin-fixed) (0.25-0.5ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.
PC12 cells. Adrenal gland, bowel, parathyroid, pancreas, or pheochromocytoma.
200ug/ml of Ab purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
This antibody is available for research use only and is not approved for use in diagnosis.
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.