|Catalog No||Formulation||Size||Price (USD)|
|3855-RBM9-P0||Purified Ab with BSA and Azide at 200ug/ml||20 ug||199.00|
|3855-RBM9-P1||Purified Ab with BSA and Azide at 200ug/ml||100 ug||379.00|
|3855-RBM9-P2||Purified Ab with BSA and Azide at 200ug/ml||200 ug||549.00|
|3855-RBM9-P1ABX||Purified Ab WITHOUT BSA and Azide at 1.0mg/ml||100 ug||399.00|
|3855-RBM9-P2ABX||Purified Ab WITHOUT BSA and Azide at 1.0mg/ml||200 ug||579.00|
|Human Entrez Gene ID||3855|
|Human Gene Symbol||KRT7|
|Human Chromosome Location||12q13.13|
|Synonyms||CK-7, K2C7, Keratin 55K Type II Cytoskeletal, Keratin Simple Epithelial Type 1 K7, Keratin Type II Cytoskeletal 7, Krt2-7, KRT7, Sarcolectin, SCL, Type II Mesothelial Keratin K7, Type-II Keratin Kb7|
|Immunogen||Recombinant full-length human KRT7 protein|
|Host / Ig Isotype||Rabbit / IgG, kappa|
|Mol. Weight of Antigen||55kDa|
|Species Reactivity||Human. Others not known.|
It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
Flow Cytometry (0.5-1ug/million cells)
Immunohistology (Formalin-fixed) (0.5-1.0ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.
HeLa cells. Carcinoma of ovary, lung, cervix, or breast
200ug/ml of Ab purified by Protein A Column. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
This antibody is available for research use only and is not approved for use in diagnosis.
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.