HER-2 / c-erbB-2 / neu / CD340 Antibody [ERBB2/2452]

Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with HER-2 Mouse Monoclonal Antibody (ERBB2/2452).

SDS-PAGE Analysis Purified HER-2 Mouse Monoclonal Antibody (ERBB2/2452). Confirmation of Purity and Integrity of Antibody.

Analysis of Protein Array containing more than 19,000 full-length human proteins using HER-2 Mouse Monoclonal Antibody (ERBB2/2452). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Immunofluorescent staining of PFA-fixed MCF-7 cells with HER-2 Monospecific Mouse Monoclonal Antibody (HRB2/2452); followed by goat anti-mouse IgG-CF488 (Green). Nuclei are stained with Reddot (Red).

Flow Cytometric Analysis of trypsinized PFA-fixed MCF-7 cells. HER-2 Monospecific Mouse Monoclonal Antibody (HRB2/2452); followed by Goat anti-mouse IgG-CF488 (Blue); Isotype control (Red)..