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CSTF2T (Transcription Factor) Antibody [PCRP-CSTF2T-1A3]

In Stock
Catalog Number Formulation Size Price
23283-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
23283-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
23283-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol Note
Flow Cytometry (Flow)
1-2ug/million cells
Immunofluorescence (IF)
1-3ug/ml
Immunohistochemistry (IHC)
1-2ug/ml
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB)
2-4ug/ml

Summary

This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.

Product Properties & Targets

Antibody Type
Host
Mouse
Species Reactivity
Research Areas
Isotype / Light Chain
IgG2b / Kappa
Cellular Localization
Nucleus
Gene Name
Positive Control
A375, Jurkat or HeLa cells. Human colon adenocarcinoma or lung adenocarcinoma.
Immunogen
Recombinant full-length human CSTF2T protein
Alternate Names
Cleavage stimulation factor subunit 2 tau variant, CF-1 64 kDa subunit tau variant, Cleavage stimulation factor 64 kDa subunit tau variant, TauCstF-64, CF1 64 kDa subunit, tau variant; Cleavage stimulation factor 3' pre RNA, subunit 2 64kDa tau variant; Cleavage stimulation factor 64 kDa subunit tau; Cleavage stimulation factor subunit 2 tau variant; CSTF 64 kDa subunit tau

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
PCRP-CSTF2T-1A3
Chromosome Location
10q21.1
Mol. Weight of Antigen
64kDa

Functions

  • May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs (By similarity).

Key References

  • Sakamoto, H, et al. Clinical Cancer Research U.S. National Library of Medicine, Aug. 2001.

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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