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Blood Group Antigen H Type 2 (CD173) Antibody [19-OLE]

In Stock
Catalog Number Formulation Size Price
28-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
28-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
28-MSM1-P2
Purified Ab with BSA and Azide at 200ug/ml
200ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
Blood Group Antigen H Type 2 (CD173) Antibody

Formalin-paraffin human Colon Carcinoma stained with Blood Group Antigen H Type 2 MAb (19-OLE)

Applications & Dilutions

Applications Tested Dillution Protocol
Immunofluorescence (IF)
1-3ug/ml

Summary

Recognizes the blood group H type 2 antigens, trisaccharide Fuc伪1-2Gal尾1-4GlcNAc尾1 of human origin. This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunofluorescence
Species Reactivity
Human
Research Areas
Cardiovascular
Isotype / Light Chain
IgM / Kappa
Cellular Localization
Golgi apparatus, Golgi stack membrane, Secreted
Gene Name
ABO
Positive Control
KG1 cells or human colorectal carcinoma.
Immunogen
Mucinous colonic adenocarcinoma
Alternate Names
Histo-blood group ABO system transferase, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Histo-blood group A transferase, Histo-blood group B transferase, NAGAT, A transferase; ABO; B transferase; CD173; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; Histo-blood group A transferase; Histo-blood group B transferase; NAGAT

Database Links

Entrez Gene ID
28
SwissProt
P16442

Additional Information

Clone
19-OLE
Chromosome Location
9q34.2
Mol. Weight of Antigen
Multiple

Related Antibodies

View All ABO Antibodies

Functions

  • This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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