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Laminin, gamma 1 (LAMC1) Antibody [SPM193]

In Stock
Catalog Number Formulation Size Price
3915-RTM1X-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
3915-RTM1X-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
3915-RTM1X-P1ABX
Purified Ab WITHOUT BSA at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
Laminin, gamma 1 (LAMC1) Antibody

Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with Laminin Monoclonal Antibody (SPM193).

Applications & Dilutions

Applications Tested Dillution Protocol Note
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Product Properties & Targets

Antibody Type
Rat Monoclonals
Host
Rat
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry
Species Reactivity
Human, Mouse
Research Areas
Autophagy, Cardiovascular, Developmental Biology, Complement System, Lung Cancer, Signal Transduction
Isotype / Light Chain
IgG2a / Kappa
Cellular Localization
Basement membrane, Extracellular matrix, Extracellular space, Secreted
Gene Name
LAMC1
Positive Control
Normal colon or carcinomas.
Immunogen
Murine EHS laminin preparation
Alternate Names
Laminin subunit gamma-1, Laminin B2 chain, Laminin-1 subunit gamma, Laminin-10 subunit gamma, Laminin-11 subunit gamma, Laminin-2 subunit gamma, Laminin-3 subunit gamma, Laminin-4 subunit gamma, Laminin-6 subunit gamma, Laminin-7 subunit gamma, Laminin-8 subunit gamma, Laminin-9 subunit gamma, S-laminin subunit gamma, LAMB2; LAMC1; Laminin B2 chain; Laminin gamma 1; Laminin gamma 1 chain

Database Links

Entrez Gene ID
3915
SwissProt
P11047; Q5VYE7; Q6NVY8

Additional Information

Clone
SPM193
Chromosome Location
1q31
Mol. Weight of Antigen
210kDa

Related Antibodies

View All LAMC1 Antibodies

Functions

  • Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

Key References

  • Ljubimov AV et. al. Lab Investigation, 1995; 72:461-473.
  • Ljubimov AV et. al., Int J Cancer, 1992; 50:562-566.
  • Folkvord et. al., J Histochem Cytochem, 1989; 37:105-113.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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