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Formalin-fixed, paraffin-embedded human lactating breast stained with Mammaglobin Recombinant Mouse Monoclonal Antibody (rMGB/6619).
IHC analysis of formalin-fixed, paraffin-embedded human skeletal muscle. Negative tissue control using rMGB/6619 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.
SDS-PAGE Analysis of Purified Mammaglobin Recombinant Mouse Monoclonal (rMGB/6619). Confirmation of Purity and Integrity of Antibody.
Mammaglobin, 10 kDa, is a cytoplasmic protein, a mammary-specific member of the uteroglobin family. It is related to a family of epithelial secretory proteins that includes prostatein and Clara cell protein.Mammaglobin occurs in about 80% of breast carcinomas. The extend is generally larger than that of GCDFP-15. Up to 15% of nonbreast carcinomas (such as stomach, lung, colon, hepatobiliary, thyroid, ovarian, and urothelial carcinomas) have been reported positive, usually only focally. Mammaglobin is a sensitive and fairly specific marker for breast carcinoma. The panel should also include Gross cystic disease fluid protein-15 and Estrogen receptor alpha.
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