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ZNF639 / ZASC1 (Transcription Factor) Antibody [PCRP-ZNF639-2B2]

In Stock
Catalog Number Formulation Size Price
51193-MSM3-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
51193-MSM3-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
51193-MSM3-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Flow cytometric analysis of PFA-fixed HeLa cells. ZNF639 Mouse Monoclonal Antibody (PCRP-ZNF639-2B2) followed by goat anti-mouse IgG-CF488 (blue); isotype control (red).

Flow cytometric analysis of PFA-fixed HeLa cells. ZNF639 Mouse Monoclonal Antibody (PCRP-ZNF639-2B2) followed by goat anti-mouse IgG-CF488 (blue); isotype control (red).

Immunofluorescence Analysis of PFA-fixed HeLa cells stained using ZNF639 Mouse Monoclonal Antibody (PCRP-ZNF639-2B2)

Immunofluorescence Analysis of PFA-fixed HeLa cells stained using ZNF639 Mouse Monoclonal Antibody (PCRP-ZNF639-2B2)

followed by goat anti-mouse IgG-CF488 (green). CF640A phalloidin (red).

followed by goat anti-mouse IgG-CF488 (green). CF640A phalloidin (red).

SDS-PAGE Analysis ZNF639 Mouse Monoclonal Antibody (PCRP-ZNF639-2B2). Confirmation of Purity and Integrity of Antibody.

SDS-PAGE Analysis ZNF639 Mouse Monoclonal Antibody (PCRP-ZNF639-2B2). Confirmation of Purity and Integrity of Antibody.

Applications & Dilutions

Applications Tested Dillution Protocol Note
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

This gene encodes a member of the Kruppel-like zinc finger family of proteins. Amplification and overexpression of this gene have been observed in esophageal squamous cell carcinoma. The encoded protein has been shown to bind DNA in a sequence-specific manner and may regulate HIV-1 gene expression. Alternative splicing results in multiple transcript variants.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
ELISA, Flow Cytometry, Immunofluorescence, Western Blot
Species Reactivity
Human
Research Areas
Nuclear Marker
Isotype / Light Chain
IgG2a /
Cellular Localization
Nucleus
Gene Name
ZNF639
Positive Control
Colon, HeLa cells. Human fetal gut, liver or heart.
Immunogen
Recombinant human fragment (aa 406-485) ofZNF639protein
Alternate Names
Zinc finger protein 639, Zinc finger protein ANC_2H01, Zinc finger protein ZASC1, MGC157200; ZASC1; Zfp639; Zinc finger amplified in esophageal squamous cell carcinomas 1; Zinc finger protein 639; Zinc finger protein ANC 2H01; Zinc finger protein ZASC1; ZNF 639; Znf639; ZNF639 zinc finger protein 639

Database Links

Entrez Gene ID
51193
SwissProt
Q9UID6

Additional Information

Clone
PCRP-ZNF639-2B2
Chromosome Location
3q27.1
Mol. Weight of Antigen
56.05kDa

Related Antibodies

View All ZNF639 Antibodies

Functions

  • Binds DNA and may function as a transcriptional repressor.

Key References

  • Bogaerts S, et al. Nuclear translocation of alphaN-catenin by the novel zinc finger transcriptional repressor ZASC1.Exp Cell Res, 2005 Nov 15. PMID 16182284.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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