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Tubulin, beta Antibody [TUBB/4470]

In Stock
Catalog Number Formulation Size Price
203068-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
203068-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
203068-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
SDS-PAGE Analysis of Purified Tubulin beta 3 Mouse Monoclonal Antibody (TUBB/4470). Confirmation of Purity and Integrity of Antibody.

SDS-PAGE Analysis of Purified Tubulin beta 3 Mouse Monoclonal Antibody (TUBB/4470). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded prostate stained with Tubulin beta 3 Mouse Monoclonal Antibody (TUBB/4470).

Formalin-fixed, paraffin-embedded prostate stained with Tubulin beta 3 Mouse Monoclonal Antibody (TUBB/4470).

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.Ubiquitously expressed with highest levels in spleen, thymus and immature brain.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry
Species Reactivity
Human
Research Areas
Immunology, Neuroscience, Infectious Disease
Isotype / Light Chain
IgG2b / Kappa
Cellular Localization
Cytoplasm
Gene Name
TUBB
Positive Control
Human brain and spleen.
Immunogen
Recombinant full-length human Tubulin beta 5 protein (TUBB5)
Alternate Names
Tubulin beta chain, Tubulin beta-5 chain, Beta 4 tubulin; Beta 5 tubulin; beta Ib tubulin; Beta1 tubulin; Class I beta tubulin; M40; OK/SW cl.56; TUBB1; TUBB2; TUBB5; tubulin beta 1 chain; Tubulin beta 2 chain; tubulin beta 5 chain; Tubulin beta chain; Tubulin beta class I; tubulin beta polypeptide; Tubulin beta-5 chain

Database Links

Entrez Gene ID
203068
SwissProt
P07437

Additional Information

Clone
TUBB/4470
Chromosome Location
16q24.3
Mol. Weight of Antigen
55kDa

Related Antibodies

View All TUBB Antibodies

Functions

  • Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

Key References

  • Osborn M et. al. European Journal of Cell Biology. 1984; 34:137-143.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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