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ZNF804A Antibody [ZNF804A/8945]

In Stock
Catalog Number Formulation Size Price
91752-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$249.00
91752-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$539.00
91752-MSM2-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$539.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
ZNF804A Antibody

Formalin-fixed, paraffin-embedded human skeletal muscle stained with ZNF804A Mouse Monoclonal Antibody (ZNF804A/8945). Inset: PBS instead of primary antibody; secondary only negative control.

ZNF804A Antibody - Image 2

SDS-PAGE Analysis of Purified ZNF804A Mouse Monoclonal Antibody (ZNF804A/8945). Confirmation of Purity and Integrity of Antibody.

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF804A (zinc-finger protein 804A) is a 1,209 amino acid protein that contains one C2H2-type zinc finger. ZNF804A interacts with Ataxin-1, a protein that is involved in RNA metabolism. The gene encoding ZNF804A maps to human chromosome 2, which consists of 237 million bases and encodes over 1,400 genes, making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry
Species Reactivity
Human
Isotype / Light Chain
IgG2a / Kappa
Cellular Localization
Nucleus.
Gene Name
ZNF804A
Positive Control
HeLa cells. Human brain, lymph node, thyroid or small intestine.
Immunogen
Recombinant full-length human ZNF804A protein
Alternate Names
Zinc finger protein 804A

Database Links

Entrez Gene ID
91752
SwissProt
Q7Z570.3

Additional Information

Clone
ZNF804A/8945
Chromosome Location
2q32.1
Mol. Weight of Antigen
137kDa

Related Antibodies

View All ZNF804A Antibodies

Key References

  • Sjblom, T., et al. 2006. The consensus coding sequences of human breast and colorectal cancers. Science 314: 268-274.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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