TG Antibodies

Thyroglobulin (TG) is primarily expressed in the thyroid gland. It is produced by thyroid follicular cells and stored in the thyroid colloid as a reservoir for thyroid hormone synthesis. This large glycoprotein serves as a precursor in the synthesis of thyroid hormones thyroxine (T4) and triiodothyronine (T3).

Thyroglobulin is not directly associated with diseases, but its measurement in blood can be used as a tumor marker in thyroid cancer. Moreover, monitoring thyroglobulin levels after thyroidectomy can help detect the recurrence of thyroid cancer.

Antibodies against thyroglobulin, particularly immunoassays, are used in clinical settings to measure serum TG levels. In thyroid cancer, monitoring changes in serum thyroglobulin levels can aid in the detection of residual or recurrent disease.

Synonyms

Thyroglobulin, AITD3; hTG; TDH3; Tg; Tgn

Research Areas

Apoptosis, Autophagy, Breast Cancer, Cancer, Cardiovascular, Cell Biology, Cellular Markers and Tags, Developmental Biology, Endocrine, Epigenetics, Gastrointestinal Tract, Hypoxia, Immuno Oncology, Immunology, Kidney, Lymphatic, Metabolism, Microbiology, Muscle, Neuroscience, Pancreatic Cancer, Prostate Cancer, Skin, Stem Cell, AKT Signaling, Angiogenesis, Articular Cartilage Extracellular Matrix, B Cell Markers, Basal Cell Marker, BBB VCAM-1 Signaling, Bladder Cancer, Cardiac Stem Cells, Colon Cancer, Complement System, CTLA-4 blockade immunotherapy, Cytokine Signaling, Defective Intrinsic Apoptosis, Dendritic Cell Marker, Digestion, Endothelial Cell Marker, Hematopoietic Stem Cells, Immune checkpoint, Infectious Disease, Lipid Metabolism, Lung Cancer, MAPK Signaling, Mast Cell Marker, Mesenchymal Stem Cell Differentiation, Mitochondria Marker, Neural Stem Cells, Neuroinflammation, Nuclear Marker, Oncology, Ovarian Cancer, PD-1 blockade immunotherapy, Signal Transduction, Stem Cell Differentiation, Transcription Factors