Thy-1 Antibodies

Thy-1 (THY1 or CD90) is a glycoprotein with a molecular weight of around 25-37 kDa, depending on the glycosylation state and post-translational modifications. This protein is expressed on the surface of various cell types, including certain subsets of T cells, neurons, fibroblasts, endothelial cells, and hematopoietic stem cells. The precise function of THY1 is complex and varies among different cell types. For example, it may play a role in neurite outgrowth and synaptic plasticity in neurons.

Thy-1 has been implicated in certain pathological conditions, including fibrosis and neurodegenerative diseases. Additionally, changes in its expression have been observed in conditions such as multiple sclerosis and Alzheimer’s disease.

Antibodies against Thy-1 are commonly used in research to study the expression and function of THY1 in various cell types. They are valuable tools for immunohistochemistry, flow cytometry, and other techniques to identify and characterize Thy-1-positive cells. In some cases, its expression (or alterations in its expression) may be investigated as potential biomarkers for certain diseases.

Synonyms

Thy-1 membrane glycoprotein, Thy-1 antigen, CD90; Theta antigen; Thy 1 cell surface antigen; Thy 1 membrane glycoprotein; Thy 1.2; Thy-1 antigen; Thy-1 membrane glycoprotein; Thy1; Thy1 T cell antigen; Thy1.1; Thy1.2; Thymus cell antigen 1, theta

Research Areas

Apoptosis, Autophagy, Breast Cancer, Cancer, Cardiovascular, Cell Biology, Cellular Markers and Tags, Developmental Biology, Endocrine, Epigenetics, Gastrointestinal Tract, Hypoxia, Immuno Oncology, Immunology, Kidney, Lymphatic, Metabolism, Microbiology, Muscle, Neuroscience, Pancreatic Cancer, Prostate Cancer, Skin, Stem Cell, AKT Signaling, Angiogenesis, Articular Cartilage Extracellular Matrix, B Cell Markers, Basal Cell Marker, BBB VCAM-1 Signaling, Bladder Cancer, Cardiac Stem Cells, Colon Cancer, Complement System, CTLA-4 blockade immunotherapy, Cytokine Signaling, Defective Intrinsic Apoptosis, Dendritic Cell Marker, Endothelial Cell Marker, Hematopoietic Stem Cells, Immune checkpoint, Infectious Disease, Lung Cancer, MAPK Signaling, Mast Cell Marker, Mesenchymal Stem Cell Differentiation, Mitochondria Marker, Neural Stem Cells, Neuroinflammation, Nuclear Marker, Ovarian Cancer, PD-1 blockade immunotherapy, Signal Transduction, Stem Cell Differentiation, Transcription Factors