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BSA (Bovine Serum Albumin) Antibody [ALB/398]

In Stock
Catalog Number Formulation Size Price
CW280717-MSM1-P0
Purified Ab with Azide at 200ug/ml
20ug
$229.00
CW280717-MSM1-P1
Purified Ab with Azide at 200ug/ml
100ug
$519.00
CW280717-MSM1-P1AX
Purified Ab WITHOUT Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day

Summary

Reacts with a protein of ~66kDa, identified as bovine serum albumin (BSA). It is a high affinity antibody and can be used for detection of traces of BSA. Bovine serum albumin (BSA) is an abundant plasma protein in cows that is important for maintaining osmotic pressure in blood plasma for proper distribution of body fluids between intravascular compartments and body tissues. BSA is a common buffer component for immunoglobulin type assays due to good solubility characteristics for water, Ca2+, Na+, K+, fatty acids, hormones and bilirubin. BSA makes up about half of the protein in plasma and represents the most stable and soluble protein in the plasma. It is a suitable reagent for laboratories developing immunoassays, mostly due to its availability, solubility and the numerous functional groups present for coupling. The BSA component contains several lysine that are capable of reacting with conjugation sites of linkers, making it applicable as a carrier protein for antigenic compounds.

Product Properties & Targets

Antibody Type
Host
Mouse
Applications
Species Reactivity
Cow
Isotype / Light Chain
IgG1 / Kappa
Cellular Localization
Secreted
Gene Name
ALB
Positive Control
Bovine serum albumin. Cow liver.
Immunogen
Purified bovine serum albumin
Alternate Names
Albumin, BSA, ALB; BSA; Growth inhibiting protein 20

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
ALB/398
Mol. Weight of Antigen
66kDa

Functions

  • Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (PubMed:22677715). The shared binding site between zinc and calcium at residue Asp-272 suggests a crosstalk between zinc and calcium transport in the blood (Probable). The rank order of affinity is zinc > calcium > magnesium (Probable). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed:6234017). Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed:6234017).

Key References

  • Haroun, M. 2005. Bovine serum albumin antibodies as a disease marker for hepatitis E virus infection. J. Biomed. Biotechnol. 2005: 316-321.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% azide. Also available WITHOUT azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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