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CD38 (ADP Ribosyl Cyclase I) Antibody [AT2]

In Stock
Catalog Number Formulation Size Price
952-MSM5-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
952-MSM5-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
952-MSM5-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
CD38 Antibody in SDS-PAGE

CD38 Antibody in SDS-PAGE

SDS-PAGE Analysis of Purified CD38 Mouse Monoclonal Antibody (AT-2). Confirmation of Purity and Integrity of Antibody.

Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml

Summary

This MAb reacts with a 45kDa glycopeptide, which is a type II membrane glycoprotein with a transmembrane sequence near the NH2terminus. CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34+ cells. The CD34+CD38- population of hematopoietic stems cells defines the most pluripotent cells (e.g. blast colony forming cells).

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunofluorescence
Species Reactivity
Human
Research Areas
Hypoxia, B Cell Markers, Hematopoietic Stem Cells
Isotype / Light Chain
IgG3 / Kappa
Cellular Localization
Membrane
Gene Name
CD38
Positive Control
CCRF-CEM cells, Spleen or Skin., Tonsil
Immunogen
Human T cell line CCRF-CEM
Alternate Names
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, Acute Lymphoblastic Leukemia Cells Antigen; ADP Ribosyl Cyclase 1; cADP-ribose Hydrolase 1; CD38H; NAD(+) Nucleosidase; NIM-R5 Antigen; p45; T10

Database Links

Entrez Gene ID
952
SwissProt
P28907

Additional Information

Clone
AT2
Chromosome Location
4p15
Mol. Weight of Antigen
~45kDa (Glycoprotein); 35kDa (protein core)

Related Antibodies

View All CD38 Antibodies

Functions

  • Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

Key References

  • Deaglio S et. al. J Immunol. 1998;160(1):395-402.

PubMed Links

Storage & Stability

Store at 2 to 8°C. Antibody is stable for 24 months.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

0.5 ml at 200 �g/ml of antibody Purified from Bioreactor Concentrate by Protein A/G chromatography. Supplied in 10mM PBS, pH 7.4 with 0.05% BSA and 0.05% sodium azide. Contact us if you require this antibody in a different format.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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