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GDF8 (Growth Differentiation Factor 8) / Myostatin Antibody [GDF9/4261]

In Stock
Catalog Number Formulation Size Price
2660-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
2660-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
2660-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day
SDS-PAGE Analysis of Purified GDF8 / Myostatin Mouse Monoclonal Antibody (MSTN/4254) Confirmation of Integrity and Purity of Antibody.

SDS-PAGE Analysis of Purified GDF8 / Myostatin Mouse Monoclonal Antibody (MSTN/4254) Confirmation of Integrity and Purity of Antibody.

Applications & Dilutions

Applications Tested Dillution Protocol Note
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Myostatin is a well-characterized negative regulator of skeletal muscle and can inhibit myogenesis and stimulate adipogenesis. Clone Myo 2/1A has been shown to have the reverse effect, up- regulate myogenesis and down- regulate adipogenesis.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
ELISA, Western Blot
Species Reactivity
Human
Research Areas
Cardiovascular, Transcription Factors
Isotype / Light Chain
IgG /
Cellular Localization
Secreted
Gene Name
MSTN
Positive Control
Muscle fiber.
Immunogen
Recognizes the 113 amino acid carboxy-terminal fragment of Myostatin protein
Alternate Names
Growth/differentiation factor 8, Myostatin, Growth/differentiation factor 8, GDF-8, GDF8, MSTN, MSLHP

Database Links

Entrez Gene ID
2660
SwissProt
O14793

Additional Information

Clone
GDF9/4261
Chromosome Location
2q32.2
Mol. Weight of Antigen
52kDa

Related Antibodies

View All MSTN Antibodies

Functions

  • Acts specifically as a negative regulator of skeletal muscle growth.

Key References

  • Artaza, J.N., et al. (2005) Myostatin Inhibits Myogenesis and Promotes Adipogenesis in C3H 10T (1/2) Mesenchymal Multipotent Cells. Endocrinology; 146 (8): 3547- 3557.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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