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Recombinant Heart Fatty Acid Binding Protein (H-FABP) / FABP3 Antibody [FABP3/8343R]

In Stock
Catalog Number Formulation Size Price
2170-RBM6-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
2170-RBM6-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
2170-RBM6-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
Recombinant Heart Fatty Acid Binding Protein (H-FABP) / FABP3 Antibody

Formalin-fixed, paraffin-embedded human heart stained with FABP3 Recombinant Rabbit Monoclonal Antibody (FABP3/8343R). HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants.

Product Properties & Targets

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry
Species Reactivity
Human
Research Areas
Cardiovascular, Mesenchymal Stem Cell Differentiation
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Cytoplasm.
Gene Name
FABP3
Positive Control
Human heart or skeletal muscle.
Immunogen
Human recombinant FABP3 protein fragment (around aa1-127) (exact sequence is proprietary)
Alternate Names
Fatty acid-binding protein, heart, Fatty acid-binding protein 3, Heart-type fatty acid-binding protein, Mammary-derived growth inhibitor, Muscle fatty acid-binding protein, 422 protein; Cardiac Fatty Acid Binding Protein; Fatty acid binding protein 11 (FABP11); Fatty acid binding protein 3, muscle and heart (mammary derived growth inhibitor); H-FABP; Heart type fatty acid binding protein; M FABP; Mammary derived growth inhibitor; MDGI; Muscle fatty acid binding protein; Mylein protein P2 homolog / adopocyte

Database Links

Entrez Gene ID
2170
SwissProt
P05413

Additional Information

Clone
FABP3/8343R
Chromosome Location
2p11.2
Mol. Weight of Antigen
15kDa

Related Antibodies

View All FABP3 Antibodies

Functions

  • FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.

Key References

  • Watanabe, K., et al. (1993). Immunohistochemical distribution of heart-type fatty acid-binding protein immunoreactivity in normal human tissues and in acute myocardial infarct. The Journal of pathology, 170(1), 59-65. https://doi.org/10.1002/path.1711700110

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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