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Human Herpes Virus 8 (HHV8) Antibody [LN53]

In Stock
Catalog Number Formulation Size Price
RTM1-1746-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
RTM1-1746-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
RTM1-1746-P1ABX
Purified Ab WITHOUT BSA at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
Human Herpes Virus 8 (HHV8) Antibody

SDS-PAGE Analysis of Purified HHV8 Rat Monoclonal Antibody (LN53). Confirmation of Purity and Integrity of Antibody.

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunofluorescence (IF)
1-3ug/ml
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.

Product Properties & Targets

Antibody Type
Rat Monoclonals
Host
Rat
Applications
ELISA, Immunofluorescence, Immunohistochemistry
Species Reactivity
Species Independent
Isotype / Light Chain
IgG2c / Kappa
Cellular Localization
N/A
Gene Name
N/A
Positive Control
Kaposi's sarcoma. Cultured cells infected with HHV8.
Immunogen
Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8
Alternate Names
N/A, N/A, HHV8; Human Herpes Virus 8; Human herpesvirus 8; Kaposi's sarcoma associated herpes virus; KSHV

Database Links

Entrez Gene ID
Not Applicable
SwissProt
N/A

Additional Information

Clone
LN53
Chromosome Location
Not Applicable
Mol. Weight of Antigen
Not Known

Related Antibodies

View All N/A Antibodies

Functions

  • N/A

Key References

  • Dupin et al. Proc. Natl. Acad. Sci. USA 96: 4546, 1999.
  • Ablashi et al. Clinc Microbiol Reviews 15: 439, 2002
  • Kellam et al. J Virol 73: 5149, 1999.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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