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ID4 Antibody [PCRP-ID4-1A1]

In Stock
Catalog Number Formulation Size Price
3400-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$249.00
3400-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$539.00
3400-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$539.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol Note
Western Blot (WB)
2-4ug/ml

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Product Properties & Targets

Antibody Type
Host
Mouse
Applications
Species Reactivity
Research Areas
Isotype / Light Chain
IgG1 /
Cellular Localization
Nucleus.
Gene Name
ID4
Positive Control
HeLa or U87 cells.
Immunogen
Recombinant fragment (around aa 62-112) of human ID4 protein
Alternate Names
DNA-binding protein inhibitor ID-4, Class B basic helix-loop-helix protein 27, Inhibitor of DNA binding 4, Inhibitor of differentiation 4, bHLHb27; Class B basic helix-loop-helix protein 27; DNA binding protein inhibitor ID4; ID 4; Id4; IDB4; Inhibitor of DNA binding 4; Inhibitor of DNA binding 4 dominant negative helix loop helix protein

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
PCRP-ID4-1A1
Chromosome Location
6p22.3
Mol. Weight of Antigen
16.6kDa

Functions

  • Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation (By similarity).

Key References

  • Blackshaw S., et al. Nature methods15.5 (2018 May): 330-338.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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