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LAMP5 (Late Endosomes Marker) Antibody [LAMP5/7642]

In Stock
Catalog Number Formulation Size Price
24141-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
24141-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
24141-MSM2-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
LAMP5 (Late Endosomes Marker) Antibody

Formalin-fixed, paraffin-embedded human kidney stained with LAMP5 Mouse Monoclonal Antibody (LAMP5/7642). Inset: PBS instead of primary antibody; secondary only negative control.

LAMP5 (Late Endosomes Marker) Antibody - Image 2

SDS-PAGE Analysis of Purified LAMP5 Mouse Monoclonal Antibody (LAMP5/7642). Confirmation of Purity and Integrity of Antibody.

LAMP5 (Late Endosomes Marker) Antibody - Image 3

Western blot analysis of U937 cell lysate using LAMP5 Mouse Monoclonal Antibody (LAMP5/7642).

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-5, also known as C20orf103, is a 280 amino acid protein that belongs to the LAMP family and is mainly found in cytoplasmic vesicles of the neuronal cell body. LAMP-5 is up-regulated upon CpG activation and down-regulated up Toll-like receptor (TLR) ligands.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG2 / Kappa
Cellular Localization
Cell Surface. Lysosome.
Gene Name
LAMP5
Positive Control
Human brain.
Immunogen
Recombinant full-length human LAMP5 protein
Alternate Names
Lysosome-associated membrane glycoprotein 5, Brain and dendritic cell-associated LAMP, Brain-associated LAMP-like protein, Lysosome-associated membrane protein 5, Lysosome-Associated Membrane Glycoprotein 5

Database Links

Entrez Gene ID
24141
SwissProt
Q9UJQ1

Additional Information

Clone
LAMP5/7642
Chromosome Location
20p12.2
Mol. Weight of Antigen
27/31 kDa

Related Antibodies

View All LAMP5 Antibodies

Functions

  • Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain.

Key References

  • Febbraio, M., et al. 1990. Identification and characterization of LAMP-1 as an activation-dependent platelet surface glycoprotein. J. Biol. Chem. 265: 18531-18537.
  • 4

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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