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Malate dehydrogenase 1 NAD (soluble) Antibody [CPTC-MDH1-1]

In Stock
Catalog Number Formulation Size Price
4190-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
4190-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
4190-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
Malate dehydrogenase 1 NAD (soluble) Antibody

SDS-PAGE Analysis of Purified MDH1 Mouse Monoclonal Antibody (CPTC-MDH1-1). Confirmation of Purity and Integrity of Antibody.

Malate dehydrogenase 1 NAD (soluble) Antibody - Image 2

Western Blot Analysis of HeLa, HepG2, Jurkat, HEP2, U937, PC3 cell lysates using MDH1 Mouse Monoclonal Antibody (CPTC-MDH1-1).

Applications & Dilutions

Applications Tested Dillution Protocol
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG2a / Kappa
Cellular Localization
Cytoplasm
Gene Name
MDH1
Positive Control
Jurkat or HeLa cell lysates.
Immunogen
Recombinant human full-length MDH1 protein
Alternate Names
Malate dehydrogenase, cytoplasmic, Cytosolic malate dehydrogenase, Diiodophenylpyruvate reductase, Cytosolic malate dehydrogenase, Diiodophenylpyruvate reductase, HEL-S-32, MDH-s, MDHA; MDH1; soluble malate dehydrogenase

Database Links

Entrez Gene ID
4190
SwissProt
P40925

Additional Information

Clone
CPTC-MDH1-1
Chromosome Location
2p15
Mol. Weight of Antigen
36kDa

Related Antibodies

View All MDH1 Antibodies

Functions

  • Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH (PubMed:3052244). Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation (PubMed:31538237).

Key References

  • Drmota, T., et al. 1997.. Folia Parasitol. 44: 103-108.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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