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Myeloid-Associated Differentiation Marker (MYADM) Antibody [MYADM/971]

In Stock
Catalog Number Formulation Size Price
91663-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
91663-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
91663-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
Myeloid-Associated Differentiation Marker (MYADM) Antibody

Formalin-fixed, paraffin-embedded human Tonsil stained with MYADM Mouse Monoclonal Antibody (MYADM/971).

Myeloid-Associated Differentiation Marker (MYADM) Antibody - Image 2

SDS-PAGE Analysis of Purified MYADM Mouse Monoclonal Antibody (MYADM/971). Confirmation of Purity and Integrity of Antibody.

Applications & Dilutions

Applications Tested Dillution Protocol Note
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Recognizes a myeloid associated differentiation antigen in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell type in human tissues. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of human and monkey myeloid cells. This MAb is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry
Species Reactivity
Human, Macaque Monkey
Isotype / Light Chain
IgG1 / Kappa
Cellular Localization
Membrane
Gene Name
MYADM
Positive Control
HL60 cells. Tonsil or lymph node.
Immunogen
Recombinant full-length human MYADM protein.
Alternate Names
Myeloid-associated differentiation marker, Protein SB135, MYADM; myeloid associated differentiation marker; Myeloid upregulated protein; Protein SB135

Database Links

Entrez Gene ID
91663
SwissProt
Q96S97

Additional Information

Clone
MYADM/971
Chromosome Location
19q13.42
Mol. Weight of Antigen
Unknown

Related Antibodies

View All MYADM Antibodies

Key References

  • Membrane protein hMYADM preferentially expressed in myeloid cells is up-regulated during differentiation of stem cells and myeloid leukemia cells. Wang Q, et al. Life Sci, 2007 Jan 9. PMID 17097684
  • Cloning of human myeloid-associated differentiation marker (MYADM) gene whose expression was up-regulated in NB4 cells induced by all-trans retinoic acid. Cui W, et al. Mol Biol Rep, 2001. PMID 12075932

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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