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Recombinant NUT1 / NUTM1 / Snurportin 1 Antibody [SNUPN/7363R]

In Stock
Catalog Number Formulation Size Price
10073-RBM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
10073-RBM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
10073-RBM2-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
SDS-PAGE Analysis of Purified NUTM1 Recombinant Rabbit Monoclonal Antibody (SNUPN/7363R). Confirmation of Purity and Integrity of Antibody.

SDS-PAGE Analysis of Purified NUTM1 Recombinant Rabbit Monoclonal Antibody (SNUPN/7363R). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human testis stained with NUTM1 Recombinant Rabbit Monoclonal Antibody (SNUPN/7363R). Inset: PBS instead of primary antibody; secondary only negative control.

Formalin-fixed, paraffin-embedded human testis stained with NUTM1 Recombinant Rabbit Monoclonal Antibody (SNUPN/7363R). Inset: PBS instead of primary antibody; secondary only negative control.

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

NUTM1 (NUT Midline Carcinoma Family Member 1) is a Protein Coding gene. Diseases associated with NUTM1 include Nut Midline Carcinoma and Spindle Cell Sarcoma. Among its related pathways are Chromatin Regulation / Acetylation. An important paralog of this gene is NUTM2G.Plays a role in the regulation of proliferation. Regulates TERT expression by modulating SP1 binding to TERT promoter binding sites.

Product Properties & Targets

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry
Species Reactivity
Human
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Nucleus. Cytoplasm.
Gene Name
NUTM1
Positive Control
Human testis.
Immunogen
Recombinant fragment (around aa 900-1100) of human NUTM1 protein (exact sequence is proprietary)
Alternate Names
NUT family member 1, Nuclear protein in testis, NUT; Nuclear Protein in Testis; C15orf55; FAM22H; NUT Family Member 1; DKFZp434O192; Chromosome 15 Open Reading Frame 55

Database Links

Entrez Gene ID
10073
SwissProt
Q86Y26

Additional Information

Clone
SNUPN/7363R
Chromosome Location
15q24.2
Mol. Weight of Antigen
120kDa

Related Antibodies

View All NUTM1 Antibodies

Functions

  • Plays a role in the regulation of proliferation. Regulates TERT expression by modulating SP1 binding to TERT promoter binding sites.

Key References

  • Luo, W., et al.NUTM1-Rearranged NeoplasmsA Heterogeneous Group of Primitive Tumors with Expanding Spectrum of Histology and Molecular AlterationsAn Updated Review.Curr. Oncol.2021,28, 4485-4503. https://doi.org/10.3390/curroncol28060381

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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