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Recombinant Parvalbumin / PVALB Antibody [PVALB/12610R]

In Stock
Catalog Number Formulation Size Price
5816-RBM4-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
5816-RBM4-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
5816-RBM4-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
Parvalbumin Antibody in Immunohistochemistry (IHC (P))

Parvalbumin Antibody in Immunohistochemistry (IHC (P))

Formalin-fixed, paraffin-embedded human kidney stained with Parvalbumin Recombinant Rabbit Monoclonal Antibody (PVALB/12610R). Inset: PBS instead of primary antibody; secondary only negative control.

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Parvalbumin alpha is a low molecular weight calcium-bound albumin (usually 9-11 kDa), structurally related to calmodulin and troponin C, and is a stable protein involved in calcium signaling. Parvalbumin is involved in physiological processes such as cell cycle regulation, second messenger production, muscle contraction, microtubule organization and light conduction. Parvalbumin alpha is found in rapidly contracting muscles, where its levels are highest, as well as in the brain and some endocrine tissues. In normal kidneys, parvoprotein has been shown to be confined to distal tubule cells and collecting tubule cells (intercellular cells).

Product Properties & Targets

Antibody Type
Rabbit Monoclonals, Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Research Areas
Neuroscience
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Cell junction, Nucleus
Gene Name
PVALB
Positive Control
Human brain, heart or kidney.
Immunogen
Recombinant full-length human PVALB protein
Alternate Names
Parvalbumin alpha, PVALB; Parvalbumin alpha

Database Links

Entrez Gene ID
5816
SwissProt
P20472

Additional Information

Clone
PVALB/12610R
Chromosome Location
22q12.3
Mol. Weight of Antigen
12kDa

Related Antibodies

View All PVALB Antibodies

Functions

  • In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

Key References

  • Tong, Y., et al. 2005. Suppression of expression of muscle-associated proteins by PPARα in brown adipose tissue. Biochem. Biophys. Res. Commun. 336: 76-83.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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