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S100A14 (S100 calcium binding protein A14) Antibody [S100A14/7401]

In Stock
Catalog Number Formulation Size Price
57402-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
57402-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
57402-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
SDS-PAGE Analysis of Purified S100A14 Mouse Monoclonal Antibody (S100A14/7401). Confirmation of Purity and Integrity of Antibody.

SDS-PAGE Analysis of Purified S100A14 Mouse Monoclonal Antibody (S100A14/7401). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human colon carcinoma stained with S100A14 Mouse Monoclonal Antibody (S100A14/7401). Inset: PBS instead of primary antibody; secondary only negative control.

Formalin-fixed, paraffin-embedded human colon carcinoma stained with S100A14 Mouse Monoclonal Antibody (S100A14/7401). Inset: PBS instead of primary antibody; secondary only negative control.

Formalin-fixed, paraffin-embedded human bladder stained with S100A14 Mouse Monoclonal Antibody (S100A14/7401). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Formalin-fixed, paraffin-embedded human bladder stained with S100A14 Mouse Monoclonal Antibody (S100A14/7401). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Formalin-fixed, paraffin-embedded human normal colon stained with S100A14 Mouse Monoclonal Antibody (S100A14/7401). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Formalin-fixed, paraffin-embedded human normal colon stained with S100A14 Mouse Monoclonal Antibody (S100A14/7401). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
ELISA, Immunohistochemistry
Species Reactivity
Human
Research Areas
Basal Cell Marker
Isotype / Light Chain
IgG2a / Kappa
Cellular Localization
Cytoplasm.
Gene Name
S100A14
Positive Control
Human colon|kidney or liver.|thymus
Immunogen
Recombinant full-length human S100A14 protein
Alternate Names
Protein S100-A14, S100 calcium-binding protein A14, BCMP84; Protein S100-A14; S100 calcium-binding protein A14; S100a14; S100A15; S10AE_HUMAN; S114

Database Links

Entrez Gene ID
57402
SwissProt
Q9HCY8

Additional Information

Clone
S100A14/7401
Chromosome Location
1q21.1
Mol. Weight of Antigen
11kDa

Related Antibodies

View All S100A14 Antibodies

Functions

  • Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.

Key References

  • Qian, Jingfeng et al. Overexpression of S100A14 in human serous ovarian carcinoma. Oncology letters vol. 11,2 (2016): 1113-1119. doi:10.3892/ol.2015.3984

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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