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SFMBT2 Antibody [PCRP-SFMBT2-2E12]

In Stock
Catalog Number Formulation Size Price
57713-MSM3-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
57713-MSM3-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
57713-MSM3-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Immunofluorescence (IF)
1-3ug/ml

Summary

The SFMBT2 (Scm-like with four MBT domains 2) gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. Sfmbt2 is a Polycomb group (PcG) gene that maps to the proximal region of Chromosome 2, and is a putative imprinted gene. Sfmbt2 is the first imprinted gene within this region to be identified. Studies indicate that six different translocations involving proximal chromosome 2 results in lethality when present as a maternal uniparental duplication.

Product Properties & Targets

Antibody Type
Host
Mouse
Species Reactivity
Isotype / Light Chain
IgG2c /
Cellular Localization
Nucleus.
Gene Name
Positive Control
HeLa or MCF-7 cells.
Immunogen
Recombinant full-length human SFMBT2 protein
Alternate Names
Scm-like with four MBT domains protein 2, Scm-Related Gene Containing Four Mbt Domains 2; Scm-Like With 4 MBT Domains Protein 2; KIAA1617

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
PCRP-SFMBT2-2E12
Chromosome Location
10p14
Mol. Weight of Antigen
100Da

Functions

  • Transcriptional repressor of HOXB13 gene.

Key References

  • Blackshaw S, et al. Nature methods15.5 (2018 May): 330-338.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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