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Printable Datasheet

Suprabasin (SBSN) (CALB1) Antibody [SBSN/7963]

In Stock
Catalog Number Formulation Size Price
374897-MSM3-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
374897-MSM3-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
374897-MSM3-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
Formalin-fixed, paraffin-embedded human esophagus stained with Suprabasin (SBSN) Mouse Monoclonal Antibody (SBSN/7963). Inset: PBS instead of primary antibody; secondary only negative control.

Formalin-fixed, paraffin-embedded human esophagus stained with Suprabasin (SBSN) Mouse Monoclonal Antibody (SBSN/7963). Inset: PBS instead of primary antibody; secondary only negative control.

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Suprabasin (SBSN) is a 247 amino acid secreted protein that is upregulated in differentiating keratinocytes and is though to play a role in epidermal differentiation. Expressed in uterus, skin, thymus and esophagus, suprabasin is encoded by a gene that maps to human chromosome 19q13.12. Chromosome 19 consists of about 63 million bases with over 1,400 genes, making up over 2% of human genomic DNA. Chromosome 19 is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fca receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and Insulin-dependent diabetes have been linked to chromosome 19.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry
Species Reactivity
Human
Isotype / Light Chain
IgG2 / Lambda
Cellular Localization
Cytoplasm. Secreted.
Gene Name
SBSN
Positive Control
Human thymus|uterus or esophagus.
Immunogen
Recombinant fragment of human SBSN protein (exact sequence is proprietary)
Alternate Names
Suprabasin, HLAR698; Suprabasin; UNQ698

Database Links

Entrez Gene ID
374897
SwissProt
Q6UWP8

Additional Information

Clone
SBSN/7963
Chromosome Location
19q13.12
Mol. Weight of Antigen
61kDa

Related Antibodies

View All SBSN Antibodies

Key References

  • Olsen, A., et al. 1994. Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region. Genomics 23: 659-668.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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