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ZFP64 Antibody [PCRP-ZFP64-1H2]

In Stock
HuProt Validated
Catalog Number Formulation Size Price
55734-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
55734-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
55734-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol Note
Flow Cytometry (Flow)
1-2ug/million cells
Immunofluorescence (IF)
1-3ug/ml
Immunohistochemistry (IHC)
1-2ug/ml
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB)
2-4ug/ml

Summary

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZFP64 (Zinc finger protein 64), also known as ZNF338, is a 681 amino acid homolog of the mouse Zfp64 protein and is a member of the Kr ppel C2H2-type zinc-finger family. Localized to the nucleus, ZFP64 contains nine C2H2-type zinc fingers and is thought to be involved in transcriptional regulation. Four isoforms of ZFP64 exist due to alternative splicing events.

Product Properties & Targets

Antibody Type
Host
Mouse
Species Reactivity
Research Areas
Isotype / Light Chain
IgG2b /
Cellular Localization
Nucleus
Gene Name
Positive Control
HeLa or HepG2 cells.
Immunogen
Recombinant full-length human ZFP64 protein
Alternate Names
Zinc finger protein 64, Zinc finger protein 338, dJ548G19.1; dJ831D17.1; ZFP64 zinc finger protein; Zinc finger protein 338; Zinc finger protein 64; Zinc finger protein 64 homolog; Zinc finger protein 64 isoforms 1 and 2; Zinc finger protein 64 isoforms 3 and 4; ZNF338

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
PCRP-ZFP64-1H2
Chromosome Location
20q13.2
Mol. Weight of Antigen
75kDa

Functions

  • May be involved in the regulation of mesenchymal cell differentiation through transactivation of NOTCH1 target genes.

Key References

  • Mack, H.G., et al. 1997. A search for a mammalian homologue of the Drosophila photoreceptor development gene glass yields Zfp64, a zinc finger encoding gene which maps to the distal end of mouse chromosome 2. Gene 185: 11-17.

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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