Transcription factors are proteins that play a pivotal role in gene expression regulation, cell development and differentiation, cell response to signals, and disease mechanisms. They bind to specific DNA sequences, typically in the promoter or enhancer regions of genes, and can either activate or repress the transcription of those genes. Their importance lies in their ability to control when and to what extent genes are transcribed into RNA, ultimately determining the production of specific proteins within a cell.
NeoBiotechnologies has a portfolio of about 1300 transcription factor antibodies developed under an NIH Grant that enable researchers to probe the complex mechanisms that govern gene expression and provide insights that have implications for a wide range of scientific and medical applications.